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IBS
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Cell Biology Faculty
Track Leader-Brian Storrie, Ph.D.Giulia Baldini, Ph.D. (Biochemistry and Molecular Biology)
Web profile
Molecular mechanism of storage and secretion of hormones in endocrine cells; Novel therapeutics for diabetes and obesity
Gbaldini@uams.edu
Steven Barger, Ph.D. (Geriatrics)
Web profile
Cell biology of Alzheimer's disease; transcriptional regulation in neurons
bargerstevenw@uams.edu
Teresita Bellido, Ph.D. (Medicine)
Web profile
Signal transduction in bone cells. Regulation of bone cell apoptosis. Osteocyte
biology. Skeletal effects and mechanism of action of bisphosphonates, steroid
hormones, parathyroid hormone, and mechanical forces.
tmbellido@uams.edu
Helen Benes, Ph.D. (Neurobiology and Developmental Sciences)
Web profile
Insect models (fruitflies, mosquitoes) to study molecular basis for regulated gene activity, in response to gender, nutrition, aging and oxidative stress, for insight into human reproductive development, diseases of aging,
including cardiac ischemia.
beneshelen@uams.edu
Timothy Chambers, Ph.D. (Biochemistry and Molecular Biology)
Web profile
Cancer chemotherapy, apoptosis, cell signaling, cell cycle regulation
ChambersTimothyC@uams.edu
Amanda
Charlesworth, Ph.D. (Neurobiology
and Developmental Sciences)
Web profile Molecular mechanisms behind developmental processes. Signal transduction,
mRNA translation, gene expression, cell cycle control. Areas of study
include meiosis and CNS development.
charlesworthamanda@uams.edu
Marie Chow, Ph.D. (Microbiology and Immunology)
Web profile
The research program uses RNA viruses to study host physiological processes (such as RNA interference), the cell biology of the virus replication cycle (such as virus entry and exit) and the role of virus-induced immune responses in neurodegenerative diseases (such as post-polio syndrome).
chowmarie@uams.edu
Parimal Chowdhury, Ph.D. (Physiology and Biophysics)
Web profile
Mechanism of Nicotine- induced Exocrine Pancreatic injury in an Animal Model
PChowdhury@uams.edu
Paul D. Drew, Ph.D. (Neurobiology and Developmental Sciences)
Web profile
Neuroimmunology, with emphasis on multiple sclerosis.
drewpauld@uams.edu
Dana Gaddy, Ph.D. (Physiology and Biophysics)
Web profile
Our laboratory focuses on the endocrine, cellular and molecular mechanisms that govern the maintenance of the musculoskeletal system, with particular focus on the normal and pathophysiological changes associated with age, disuse, menopause, and metastatic disease.
gaddydana@uams.edu
Jill James, Ph.D. (Pediatrics)
Web profile
JamesJill@uams.edu
Michael Jennings, Ph.D. (Physiology and Biophysics)
Web profile
Transport and regulation of inorganic ions, especially sodium, potassium, chloride, and sulfate
JenningsMichaell@uams.edu
Thomas Kelly, Ph.D. (Pathology)
Web profile
Proteases and heparanases in cancer metastasis
KellyThomasJ@uams.edu
Fusun Kilic,
Ph.D. (Biochemistry and Molecular Biology)
Web profile
KilicFusun@uams.edu
Vladimir Lupashin, Ph.D. (Physiology and Biophysics)
Web profile
Molecular mechanisms of intracellular membrane trafficking
LupashinVladimirV@uams.edu
Lee Ann MacMillan-Crow, Ph.D. (Pharmacology and Toxicology)
Web profile
Our laboratory has been investigating the role that increased mitochondrial oxidant production has on the early events leading to renal dysfunction following renal preservation and warm ischemia/reperfusion (I/R) in vivo. Previous studies have suggested that inactivation of the major antioxidant within the mitochondria, manganese superoxide dismutase (MnSOD), plays a pivotal role in inducing renal injury during I/R injury. Using both cell and rodent models we are also assessing the therapeutic potential of known and novel antioxidants to alter I/R and transplantation induced renal dysfunction.
macmillancrowleea@uams.edu
Angus MacNicol, Ph.D. (Neurobiology and Developmental Sciences)
Web profile
Cell cycle control, gene expression, early vertebrate development, signal transduction
macnicolangus@uams.edu
Philip Mayeux, Ph.D. (Pharmacology and Toxicology)
Web profile
Renal epithelial cell signaling: My laboratory is studying signal transduction pathways in renal epithelial cells that result in oxidative stress (reactive oxygen and reactive nitrogen species) in response to bacterial toxins and peptide hormones.
prmayeux@uams.edu
Judit Megyesi, M.D. (Medicine)
MegyesiJuditK@uams.eduDonald Mock, M.D., Ph.D. (Biochemistry and Molecular Biology)
Web profile
Our research group uses biochemistry, molecular biology, physical chemistry, and
organic chemistry to answer questions concerning the pathogenesis of
vitamin-related birth defects and anemia of low birth weight infants.
MockDonaldM@uams.edu
Kevin D. Phelan, Ph.D. (Neurobiology and Developmental Sciences)
Web profile
Mechanisms underlying synaptic transmission between developing and adult neurons
phelankevind@uams.edu
Paul L.
Prather, Ph.D. (Pharmacology
and Toxicology) Web
profile Opioid and cannabinoid receptor signaling mechanisms; cell biology and therapeutic drug development for neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS)
PratherPaulL@uams.edu
Peter M. Price, Ph.D. (Internal Medicine)
Web profile
Role of cell-cycle events in renal failure and cellular stress
PMPrice@uams.edu
Nancy J. Rusch, Ph.D. (Pharmacology, Interdisciplinary Toxicology)
Web profile
NRusch@uams.edu
Rosalia C.M. Simmen, Ph.D. (Physiology and Biophysics)
Web profile
Regulators of gene expression in the mammary gland and uterus that are essential for proper function and development
SimmenRosalia@uams.edu
Joseph R. Stimers, Ph.D. (Pharmacology and Toxicology)
Web profile
Role of ion channels and transporters in regulating cell function in the heart, neurons, and muscle
StimersJosephR@uams.edu
Brian Storrie, Ph.D. (Physiology and Biophysics)
Web profile Research
focuses on two aspects of the secretory pathway in mammalian cells: 1)assembly
and dynamics of the Golgi apparatus using cultured HeLa cells as the model and
2)assembly and function of alpha granules in human and mouse platelets.
StorrieBrian@uams.edu
Alan Tackett, Ph.D. (Biochemistry and Molecular Biology)
Web profile
Our laboratory uses cutting-edge proteomic and biochemical tools to understand how chromatin-associated protein complexes regulate chromosome structure and thereby influence cellular mechanisms like gene transcription.
AJTackett@uams.edu
Wayne Wahls, Ph.D. (Biochemistry and Molecular Biology)
Web profile
Chromosome dynamics; meiosis; homologous recombination; chromatin; combinatorial
bZIP dimers and cellular growth control; stress-activated signal transduction
pathways.
WahlsWayneP@UAMS.edu
Patricia Wight, Ph.D. (Physiology and Biophysics)
Web profile
Developmental, cellular and molecular neurobiology; regulation of gene expression; proteomics.
pwight@uams.edu
Fang Zheng, Ph.D. (Pharmacology, Interdisciplinary Toxicology)
Web profile
Molecular and cellular mechanisms of neurotoxicity related to neurological disorders, using a multidisciplinary approach.
zhengfang@uams.edu
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